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Here is the link to official Upjohn Pharma Encyclopedia; https://www.encyclopedia.com/social-sciences-and-law/economics-business-and-labor/businesses-and-occupations/upjohn-company
According to them;
Upjohn is one of the largest ethical drug manufacturers in the United States. Recognized as a world leader in developing medicines for the treatment of central nervous system diseases, disorders, and injuries, the company also manufactures an extensive line of prescription drugs used in the treatment of conditions including heart disease, cancer, and arthritis. In the last decades of the twentieth century, the company expanded into animal Pharmaceuticals and vegetable and agronomic seeds. The company has research, manufacturing, sales, and distribution facilities in more than 200 locations worldwide.
Upjohn’s Victorian beginnings coincided with the origin of modern Pharmaceuticals. In the nineteenth century, physicians who wanted to prescribe medication for their patients were limited to two unsatisfactory choices: fluid extracts of unstable and varying potency, or drugs in pill form. Although pills were of relatively standard potency, they were so hard that they could be hammered into a board without doing damage to their coating (as one of Upjohn’s early advertising gimmicks showed); often such pills did not dissolve in the stomach and were passed by the patient. In 1885 Dr. William Upjohn solved these problems and revolutionized the drug industry when he patented a tedious process for the making of a “friable” pill capable of crumbling under the pressure of an individual’s thumb.
The image of Dr. Upjohn’s thumb crushing a pill eventually became a trademark of the Upjohn Pill and Granule Co., founded in Kalamazoo in 1886 by Upjohn and his brother Henry. A talent for Promoting its products ensured the company’s steady growth through the turn of the century. By 1893 Upjohn could be seen at the Chicago World’s Fair distributing souvenirs of its exhibit—an enormous bottle filled with colored pills. In 1903 the company shortened its name to The Upjohn Company. Quinine pills and “Phenolax Wafers” (the first candy laxative) were two of the early and successful products made by Upjohn. By 1924 the extremely popular wafers were bringing in $795,000 a year, or 21 percent of Upjohn’s sales revenue.
From the very beginning Upjohn emphasized research and development. In 1913 the company hired its first research scientist, Dr. Frederick W. Heyl. Dr. Heyl proved to be a sound investment for Upjohn. One of his developments, Citro-carbonate, an effervescent antacid, reached sales of $1 million in 1926. Heyl was also responsible for patenting a digitalis tablet called Digitora, which is used in the treatment of heart disease, and which is still sold by Upjohn today.
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